THE CLINICAL IMPORTANCE OF HYPERKALAEMIA FOLLOWING SUXAMETHONIUM ADMINISTRATION
نویسندگان
چکیده
منابع مشابه
Serum cholinesterase: effect on the action of suxamethonium following administration to a patient with cholinesterase deficiency.
Purified serum cholinesterase 90 mg was administered to a patient with cholinesterase deficiency. The effect on the action of suxamethonium was studied. The half-life (44.7 h), time constant (64.5 h), rate constant (0.0155 h-1) and distribution volume (2740 ml) of the cholinesterase activity were determined.
متن کاملSuxamethonium-induced hyperkalaemia 6 weeks after chemoradiotherapy in a patient with rectal carcinoma.
Suxamethonium causes an efflux of potassium (K+) ions by depolarizing acetylcholine receptors within the neuromuscular junction and produces a transient, small rise in serum K+ concentration in normal individuals that is usually of little clinical importance. Despite the clear efficacy and relative safety of suxamethonium in many patients, anaesthetists are also very aware that acute, severe hy...
متن کاملSuxamethonium-induced hyperkalaemia in a patient with a normal potassium level before rapid-sequence intubation.
The use of suxamethonium (succinylcholine) for rapid-sequence intubation may be limited by hyperkalaemia. Modest pre-induction hyperkalaemia is usually disregarded. We present a patient who underwent emergency surgery for a perforated peptic ulcer after being bedbound for 26 days because of a head injury. Serum potassium level was 4.0 mmol/L. The patient was intubated after injection of sedativ...
متن کاملDual block following tacrine and suxamethonium.
Tacrine and suxamethonium were used to produce muscle relaxation in 29 anaesthetized patients. Relaxation was monitored with a nerve stimulator. Post-tetanic facilitation was observed in 24 patients (83 per cent). In spite of this, operating conditions were satisfactory in 26 patients. Poor operating conditions were associated with the more severe degrees of phase II block as judged by an incre...
متن کاملHyperkalaemia.
Hyperkalaemia is defined as serum potassium concentration greater than 5.5 mmol/l. Its prevalence in the general population is unknown, but it is thought to occur in 1-10% of patients admitted to hospital.1 The rate of morbidity and mortality associated with hyperkalaemia has risen greatly with the use of drugs that target the renin-angiotensin system, and since publication 10 years ago of a ra...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1969
ISSN: 0007-0912
DOI: 10.1093/bja/41.4.311